7 facts about Malignancy
1. Definition
Malignancy is a life-threatening progressive condition.Malignant Cancer means unwanted, uncontrolled growth of cells which are structurally and functionally different from their parent cells.
2. What goes wrong?
The DNA present in the nucleus of all the cells in the body is the source of 'genetic-control' over the structure and function of each cell. When, due to some reason, the DNA is repeatedly damaged, it might undergo mutation (change) and and that 'genetic-control' is lost. Hence, the cells start dividing in a haphazard manner, only to produce more abnormal cells. This abnormal cell mass is what we call 'tumor'. It has the potential to damage to the surrounding tissues and organs, creating a 'micro-environment' of its own.
3. Proto-oncogenes and Tumor-suppressor genes.
1. Definition
Malignancy is a life-threatening progressive condition.Malignant Cancer means unwanted, uncontrolled growth of cells which are structurally and functionally different from their parent cells.
2. What goes wrong?
The DNA present in the nucleus of all the cells in the body is the source of 'genetic-control' over the structure and function of each cell. When, due to some reason, the DNA is repeatedly damaged, it might undergo mutation (change) and and that 'genetic-control' is lost. Hence, the cells start dividing in a haphazard manner, only to produce more abnormal cells. This abnormal cell mass is what we call 'tumor'. It has the potential to damage to the surrounding tissues and organs, creating a 'micro-environment' of its own.
3. Proto-oncogenes and Tumor-suppressor genes.
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| G1, S, M, G2 are the phases of a cell cycle which are regulated by the genes, mutation of which causes formation of tumor. |
